[Remission, response, and its prediction in depressive inpatients]

Psychother Psychosom Med Psychol. 2013 Jul;63(7):272-9. doi: 10.1055/s-0032-1327715. Epub 2013 Feb 26.
[Article in German]

Abstract

Using mean comparisons and effect sizes to report effects of inpatient treatment, this not reveals, how many inpatients benefit from treatment and which characteristics predict the positive outcome. Several characteristics were collected from 1 533 consecutive inpatients with an episode of depression. The pre-post-effect size in the Beck Depression Inventory was 1.29 (95%-CI: 1.23; 1.36). The rate of remission was 39.5%. The rate of response was 57.8% based on the reliable change index (RCI) and 72.4% based on the percental symptom improvement. The regression model with the RCI as outcome variable was stabile in the cross-validation. A negative predictive impact was demonstrated by the depressive symptoms at treatment beginning, whereas higher assessment of physical health and higher level of education were found to be positively associated. A consistent definition of response seems essential for cross-study and cross-methodological comparisons.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Depressive Disorder, Major / psychology
  • Depressive Disorder, Major / therapy*
  • Female
  • Health Status
  • Humans
  • Inpatients
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Psychiatric Status Rating Scales
  • Psychotherapy
  • Reproducibility of Results
  • Treatment Outcome