Abstract
We present a 49-year-old male who suffered a cerebellar infarction due to a vertebral artery dissection. The patient had taken sildenafil daily for at least 2 years for sexual enhancement. There was no sexual intercourse or traumatic event prior to symptom onset. Sildenafil intake has been associated with aortic dissection and, in the light of this report, we suggest that chronic sildenafil intake could be a risk factor for arterial dissection.
Copyright © 2012 Elsevier Ltd. All rights reserved.
MeSH terms
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Anticoagulants / administration & dosage
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Anticoagulants / pharmacology
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Cerebral Infarction / diagnostic imaging
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Cerebral Infarction / drug therapy
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Cerebral Infarction / etiology*
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Clopidogrel
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Heparin / administration & dosage
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Heparin / pharmacology
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Humans
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Magnetic Resonance Imaging
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Male
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Middle Aged
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Piperazines / adverse effects*
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Platelet Aggregation Inhibitors / administration & dosage
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Platelet Aggregation Inhibitors / pharmacology
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Purines / adverse effects
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Sildenafil Citrate
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Sulfones / adverse effects*
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Ticlopidine / administration & dosage
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Ticlopidine / analogs & derivatives
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Ticlopidine / pharmacology
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Treatment Outcome
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Ultrasonography
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Vasodilator Agents / adverse effects*
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Vertebral Artery Dissection / diagnostic imaging
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Vertebral Artery Dissection / drug therapy
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Vertebral Artery Dissection / etiology*
Substances
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Anticoagulants
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Piperazines
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Platelet Aggregation Inhibitors
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Purines
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Sulfones
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Vasodilator Agents
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Heparin
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Clopidogrel
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Sildenafil Citrate
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Ticlopidine