Host versus flu: antibodies win a round?

Christopher B Brooke; Jonathan W Yewdell

doi:10.1038/nsmb.2524

Host versus flu: antibodies win a round?

Nat Struct Mol Biol. 2013 Mar;20(3):245-6. doi: 10.1038/nsmb.2524.

Authors

Christopher B Brooke¹, Jonathan W Yewdell

Affiliation

¹ Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, Maryland, USA.

Abstract

Structural and functional analyses of three neutralizing antibodies against influenza virus H2 HA may explain why this HA subtype has disappeared from circulation in the human population and point to a potential new avenue for antiflu therapeutics.

Publication types

Comment

MeSH terms

Antibodies, Viral / immunology*
Hemagglutinin Glycoproteins, Influenza Virus / immunology*
Humans
Immunoglobulin Fab Fragments / chemistry*

Substances

Antibodies, Viral
Hemagglutinin Glycoproteins, Influenza Virus
Immunoglobulin Fab Fragments

Grants and funding

ZIA AI001055-05/ImNIH/Intramural NIH HHS/United States