Photoionization and electron radical recombination dynamics in photoactive yellow protein investigated by ultrafast spectroscopy in the visible and near-infrared spectral region

J Phys Chem B. 2013 Sep 26;117(38):11042-8. doi: 10.1021/jp311906f. Epub 2013 Apr 15.

Abstract

Photoinduced ionization of the chromophore inside photoactive yellow protein (PYP) was investigated by ultrafast spectroscopy in the visible and near-infrared spectral regions. An absorption band that extended from around 550 to 850 nm was observed and ascribed to solvated electrons, ejected from the p-hydroxycinnamic acid anion chromophore upon the absorption of two 400 nm photons. Global kinetic analysis showed that the solvated electron absorption decayed in two stages: a shorter phase of around 10 ps and a longer phase of more than 3 ns. From a simulation based on a diffusion model we conclude that the diffusion rate of the electron is about 0.8 Å(2)/ps in wild type PYP, and that the electron is ejected to a short distance of only several angstroms away from the chromophore. The chromophore-protein pocket appears to provide a water-similar local environment for the electron. Because mutations at different places around the chromophore have different effect on the electron recombination dynamics, we suggest that solvated electrons could provide a new method to investigate the local dielectric environment inside PYP and thus help to understand the role of the protein in the photoisomerization process.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Bacterial Proteins / chemistry*
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism
  • Diffusion
  • Electrons
  • Halorhodospira halophila / metabolism
  • Kinetics
  • Mutation
  • Photoreceptors, Microbial / chemistry*
  • Photoreceptors, Microbial / genetics
  • Photoreceptors, Microbial / metabolism
  • Spectrophotometry
  • Spectrophotometry, Infrared

Substances

  • Bacterial Proteins
  • Photoreceptors, Microbial
  • photoactive yellow protein, Bacteria