Risk factors for septic shock after mini-percutaneous nephrolithotripsy with holmium laser

Urology. 2013 Jun;81(6):1173-6. doi: 10.1016/j.urology.2013.01.035. Epub 2013 Mar 15.

Abstract

Objective: To evaluate the risk factors for septic shock after mini-percutaneous nephrolithotripsy (MPCNL) and provide a theoretic basis for the prevention of septic shock after MPCNL.

Methods: A total of 834 patients who underwent MPCNL from June 2004 to April 2012 were retrospectively analyzed. The χ(2) test and a logistic regression were used to identify key risk factors for septic shock after MPCNL.

Result: The incidence of septic shock after MPCNL was 2.40%. Logistic regression analysis identified female sex (odds ratio, 1.055E8; P <.001) and diabetes mellitus (odds ratio, 4.192; P = .001) as independent risk factors for post-MPCNL septic shock.

Conclusion: Female sex and diabetes mellitus are the key risk factors for septic shock after MPCNL. Routine administration of antibiotics preoperatively might reduce the incidence of septic shock.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antibiotic Prophylaxis
  • Chi-Square Distribution
  • Diabetes Complications / complications
  • Escherichia coli Infections / microbiology
  • Female
  • Humans
  • Kidney Calculi / chemistry
  • Kidney Calculi / surgery
  • Kidney Calculi / therapy*
  • Klebsiella Infections / microbiology
  • Lasers, Solid-State / therapeutic use*
  • Lithotripsy, Laser / adverse effects*
  • Logistic Models
  • Male
  • Middle Aged
  • Nephrostomy, Percutaneous / adverse effects*
  • Odds Ratio
  • Proteus Infections / microbiology
  • Pseudomonas Infections / microbiology
  • Retrospective Studies
  • Risk Factors
  • Sex Factors
  • Shock, Septic / etiology*
  • Shock, Septic / microbiology
  • Shock, Septic / prevention & control