Screening and diagnosis of micronutrient deficiencies before and after bariatric surgery

Obes Surg. 2013 Oct;23(10):1581-9. doi: 10.1007/s11695-013-0919-x.

Abstract

Background: Micronutrient deficiencies are key concerns after bariatric surgery. We describe the prevalence of perioperative testing and diagnosis of micronutrient deficiencies among a cohort of insured bariatric surgery patients.

Methods: We used claims data from seven health insurers to identify bariatric surgery patients from 2002-2008. Our outcomes were perioperative claims for vitamin D, B12, folate, and iron testing and diagnosed deficiencies. We analyzed results by bariatric surgery type: Roux-en-Y gastric bypass (RYGB), restrictive, and malabsorptive. We calculated the prevalence of testing and deficiency diagnosis, and performed multivariate logistic regression to determine the association with surgery type.

Results: Of 21,345 eligible patients, 84% underwent RYGB. The pre-surgical testing prevalence for all micronutrients was <25%. The testing prevalence during the first 12 months after surgery varied: vitamin D (12%), vitamin B12 (60%), folate (47%) and iron (49%), and declined during 13-24 and 25-36 months. The deficiency prevalence during 0-12 months post-survey varied: vitamin D (34%), vitamin B12 (20%), folate (13%), and iron (10%). The odds of vitamin B12, folate, and iron deficiency during 0-12 months were significantly lower for restrictive as compared to RYGB, but were not different during 13-24 and 25-36 months post-surgery. The odds of vitamin D deficiency were significantly greater for malabsorptive as compared to RYGB during all post-surgical periods.

Conclusion: Many patients did not receive micronutrient testing pre- or post-surgery, yet deficiencies were relatively common among those tested. These results highlight the need for surgeons and primary care providers to test all bariatric surgery patients for micronutrient deficiencies.

Publication types

  • Evaluation Study
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Female
  • Folic Acid Deficiency / blood
  • Folic Acid Deficiency / diagnosis
  • Gastric Bypass / adverse effects*
  • Humans
  • Iron / blood
  • Iron Deficiencies*
  • Male
  • Maryland / epidemiology
  • Mass Screening* / standards
  • Mass Screening* / statistics & numerical data
  • Micronutrients / blood
  • Micronutrients / deficiency*
  • Obesity, Morbid / blood*
  • Obesity, Morbid / epidemiology
  • Obesity, Morbid / surgery*
  • Postoperative Period
  • Practice Guidelines as Topic
  • Preoperative Period
  • Prevalence
  • Time Factors
  • United States / epidemiology
  • Vitamin B 12 Deficiency / blood
  • Vitamin B 12 Deficiency / diagnosis
  • Vitamin D Deficiency / blood
  • Vitamin D Deficiency / diagnosis

Substances

  • Micronutrients
  • Iron