Abstract
Different generations of perylenediimide-cored dendrimers with peripheral amine groups were synthesized. All these water-soluble dendrimers could rapidly internalize into live cells with high efficacy of gene transfection and low cytotoxicity. Increasing dendrimer generation increased their ability for gene transfection.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Animals
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Biological Transport
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Cell Line
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DNA / chemistry*
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Dendrimers / chemistry*
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Drosophila
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Fluorescence
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Fluorescent Dyes / chemistry
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Imides / chemistry*
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Perylene / analogs & derivatives*
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Perylene / chemistry
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Solubility
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Transfection
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Water / chemistry
Substances
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Dendrimers
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Fluorescent Dyes
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Imides
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perylenediimide
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Water
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Perylene
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DNA