Abstract
An enantioselective tandem reaction of chromones-derived MBH carbonates (1) with benzylamines (2) catalyzed by a trifunctional organocatalyst, cinchonidine-amide-thiourea, has been developed in moderate to good yields (50-87%) and enantioselectivities (up to 89% ee).
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amides / chemistry
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Benzylamines / chemistry*
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Carbonates / chemistry*
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Catalysis
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Chromones / chemistry
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Cinchona Alkaloids / chemistry
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Flavanones / chemical synthesis*
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Stereoisomerism
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Thiourea / chemistry
Substances
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Amides
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Benzylamines
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Carbonates
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Chromones
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Cinchona Alkaloids
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Flavanones
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cinchonidine
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Thiourea