A two-photon fluorescent probe with near-infrared emission for hydrogen sulfide imaging in biosystems

Chem Commun (Camb). 2013 May 10;49(37):3890-2. doi: 10.1039/c3cc41244j.

Abstract

Hydrogen sulfide (H2S) is emerging as an important gasotransmitter but remains difficult to study. Here we report a novel two-photon fluorescent probe with NIR emission for H2S detection. It was successfully used to realize H2S imaging in bovine serum, living cells, tissues as well as in living mice.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Benzopyrans / chemical synthesis*
  • Cattle
  • Cell Line, Tumor
  • Fluorescent Dyes / chemical synthesis*
  • Humans
  • Hydrogen Sulfide / analysis*
  • Hydrogen Sulfide / metabolism
  • Mice
  • Mice, Inbred ICR
  • Microscopy, Fluorescence
  • Molecular Imaging / methods*
  • Photons*

Substances

  • Benzopyrans
  • Fluorescent Dyes
  • Hydrogen Sulfide