[Sentinel lymph node biopsy for penile carcinoma : Assessment of reliability]

Urologe A. 2013 Oct;52(10):1447-50. doi: 10.1007/s00120-013-3166-9.
[Article in German]

Abstract

Background: The European Association of Urologists recommends dynamic sentinel node biopsy (DSNB) as the first choice diagnostic approach for lymph node staging of non-palpable inguinal lymph nodes in penile carcinoma. The aim of this study was to assess the reliability of minimally invasive inguinal DSNB.

Material and methods: Between 2004 and 2012 DSNB was used in all patients with invasive penile carcinoma and non-palpable inguinal lymph nodes. For assessment of reliability the rate of false negative results was determined and complications were documented. The results were analyzed prospectively.

Results: In the study period DSNB was performed in a total of 29 patients and it was possible to prove lymph node metastasis in 2 patients with 1 patient who developed lymph node metastasis after a negative DSNB. Thus the false negative rate was 3.70 %. A morbidity rate of 3.45 % was also observed.

Conclusion: Sentinel lymph node biopsy is a reliable diagnostic method. The sophisticated requirements both methodologically and logistically suggest that this procedure should only be performed in specialized centres.

Publication types

  • English Abstract

MeSH terms

  • Adult
  • Aged
  • Carcinoma / pathology*
  • Carcinoma / secondary*
  • Humans
  • Lymph Nodes / pathology*
  • Male
  • Middle Aged
  • Neoplasm Invasiveness
  • Penile Neoplasms / pathology*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Sentinel Lymph Node Biopsy / methods*