Total synthesis of the tubulin inhibitor WF-1360F based on macrocycle formation through ring-closing alkyne metathesis

Angew Chem Int Ed Engl. 2013 May 27;52(22):5866-70. doi: 10.1002/anie.201300576. Epub 2013 Apr 22.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry*
  • Macrocyclic Compounds / chemistry*
  • Macrolides / chemical synthesis*
  • Macrolides / chemistry
  • Molecular Structure
  • Tubulin Modulators / chemical synthesis*
  • Tubulin Modulators / chemistry
  • Vinyl Compounds / chemistry

Substances

  • Alkynes
  • Macrocyclic Compounds
  • Macrolides
  • Tubulin Modulators
  • Vinyl Compounds
  • vinyl iodide
  • rhizoxin