Nonfebrile seizures after mumps, measles, rubella, and varicella-zoster virus combination vaccination with detection of measles virus RNA in serum, throat, and urine

Clin Vaccine Immunol. 2013 Jul;20(7):1094-6. doi: 10.1128/CVI.00084-13. Epub 2013 May 1.

Abstract

We report the case of a child presenting with nonfebrile seizures 6 and 13 days after the first vaccination with a measles, mumps, rubella, and varicella (MMRV) combination vaccine. Measles virus RNA was detected in the patient's serum, throat, and urine. Genotyping revealed the Schwarz vaccine virus strain.

Publication types

  • Case Reports

MeSH terms

  • Chickenpox Vaccine / administration & dosage*
  • Chickenpox Vaccine / adverse effects*
  • Genotype
  • Humans
  • Infant
  • Male
  • Measles virus / classification
  • Measles virus / genetics*
  • Measles-Mumps-Rubella Vaccine / administration & dosage*
  • Measles-Mumps-Rubella Vaccine / adverse effects*
  • Pharynx / virology
  • RNA, Viral / blood*
  • RNA, Viral / urine*
  • Seizures / chemically induced*
  • Seizures / epidemiology*
  • Serum / virology
  • Urine / virology
  • Vaccines, Combined / administration & dosage
  • Vaccines, Combined / adverse effects

Substances

  • Chickenpox Vaccine
  • Measles-Mumps-Rubella Vaccine
  • RNA, Viral
  • Vaccines, Combined
  • measles, mumps, rubella, varicella vaccine