Epidural analgesia and its effect on umbilical artery flow velocity waveform patterns in uncomplicated labour and labour complicated by pregnancy-induced hypertension

Eur J Obstet Gynecol Reprod Biol. 1990 Jul-Aug;36(1-2):35-41. doi: 10.1016/0028-2243(90)90047-5.

Abstract

Umbilical artery flow velocity waveforms were obtained using continuous-wave Doppler ultrasound to examine the effect of epidural analgesia on peak systolic/least diastolic ratio (A/B ratio) in 38 women in uncomplicated labour, and 12 women with pregnancy-induced hypertension (PIH). In the uncomplicated group there was no significant change in A/B ratio after epidural analgesia, but in the PIH group there was significant correlation between the fall in mean blood pressure and the fall in A/B ratio at 30 min after induction of epidural analgesia (r = 0.85, p less than 0.001). This suggests that epidural analgesia in PIH is associated with a reduction in placental resistance and may be beneficial to the fetus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Analgesia, Epidural / adverse effects*
  • Blood Pressure / drug effects
  • Female
  • Heart Rate, Fetal / drug effects
  • Humans
  • Hypertension / physiopathology*
  • Labor, Obstetric*
  • Maternal-Fetal Exchange
  • Pregnancy
  • Pregnancy Complications, Cardiovascular*
  • Regional Blood Flow / drug effects
  • Ultrasonics
  • Umbilical Arteries / drug effects*