The human skin-associated autoantigen α-NAC activates monocytes and dendritic cells via TLR-2 and primes an IL-12-dependent Th1 response

J Invest Dermatol. 2013 Sep;133(9):2289-92. doi: 10.1038/jid.2013.161. Epub 2013 Apr 3.
No abstract available

Publication types

  • Letter

MeSH terms

  • Autoantigens / immunology
  • Autoantigens / metabolism*
  • Dendritic Cells / immunology
  • Dendritic Cells / metabolism*
  • Humans
  • Interleukin-12 Subunit p35 / immunology
  • Interleukin-12 Subunit p35 / metabolism*
  • Molecular Chaperones / immunology
  • Molecular Chaperones / metabolism*
  • Monocytes / immunology
  • Monocytes / metabolism*
  • Th1 Cells / immunology
  • Th1 Cells / metabolism
  • Toll-Like Receptor 2 / immunology
  • Toll-Like Receptor 2 / metabolism*

Substances

  • Autoantigens
  • IL12A protein, human
  • Interleukin-12 Subunit p35
  • Molecular Chaperones
  • TLR2 protein, human
  • Toll-Like Receptor 2
  • nascent-polypeptide-associated complex