Diagnostic value of color Doppler ultrasonography and MDCT angiography in complications of hemodialysis fistulas and grafts

Eur J Radiol. 2013 Sep;82(9):1436-43. doi: 10.1016/j.ejrad.2013.03.015. Epub 2013 May 6.

Abstract

Purpose: The purpose of the study was to compare the diagnostic value of color Doppler ultrasonography (CDUS) and multidetector computed tomography (MDCT) angiography against that of digital subtraction angiography (DSA) or surgery in the evaluation of failing hemodialysis arteriovenous fistulas (AVFs).

Materials and methods: CDUS and MDCT angiography were performed with 41 patients (24 men, 17 women; mean age 55.8) with dysfunctional hemodialysis fistulas. The presence of stenosis, thrombosis, aneurysm, pseudoaneurysm and seroma were recorded. The sensitivity, specificity, positive and negative predictive values (PPV and NPV) and accuracy of CDUS and MDCT angiography were calculated both individually and in combination for the detection of vascular segments with significant stenosis, thrombosis, aneurysms, pseudoaneurysms, perivascular complications and stenosis subgroups.

Results: Sixty-four segmental lesions were diagnosed by DSA or surgery. Sensitivity, specificity, PPV, NPV and accuracy of CDUS for all vascular tree lesions were 85.9%, 99.2%, 96.4%, 96.7% and 94.5%, respectively. For MDCT angiography the figures were 96.8%, 99.6%, 98.4%, 99.2% and 98.5%, respectively. When both tests were used in combination, sensitivity, specificity, PPV, NPV and accuracy for all vascular tree lesions rose to 100%.

Conclusion: Combined use of MDCT and CDUS for diagnosis of AVF dysfunctions is of equivalent value to surgery or DSA, a gold standard technique.

Keywords: CDUS; Digital subtraction angiography; Hemodialysis fistula; MDCT angiography.

Publication types

  • Comparative Study
  • Controlled Clinical Trial

MeSH terms

  • Adult
  • Anastomosis, Surgical / adverse effects*
  • Blood Vessel Prosthesis / adverse effects*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Models, Biological
  • Models, Statistical
  • Multidetector Computed Tomography / methods*
  • Renal Dialysis / adverse effects*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Treatment Outcome
  • Ultrasonography, Doppler, Color / methods*
  • Vascular Diseases / diagnosis*
  • Vascular Diseases / etiology*