Adenosine: essential for life but licensed to kill

Mol Cell. 2013 May 9;50(3):307-8. doi: 10.1016/j.molcel.2013.04.020.

Abstract

In this issue of Molecular Cell,Long and Crighton (2013) report a cell death priming mechanism activated by p53 that senses extracellular adenosine accumulated following chemotherapy or hypoxia, providing a novel connection between adenosine signaling and apoptosis.

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