[Optimization of preparation of salt-processed psoraleae fructus medicines with multi-index orthogonal method]

Zhongguo Zhong Yao Za Zhi. 2013 Feb;38(3):346-9.
[Article in Chinese]

Abstract

Objective: To optimize the preparation of salt-processed Psoraleae Fructus by the orthogonal test method.

Method: With the 12 components such as coumarin, flavone and phenolics as study indexes, a L9 (3(4)) orthogonal test was adopted to compare the effect of different factors on salt-processed Psoraleae Fructus.

Result: According to the finalized optimal process, 100 g Psoraleae Fructus was added with 2 g salt, moistened for 2 hours, and then fried for 10 min at 150 degrees.

Conclusion: The orthogonal test is so reasonable and reliable that it can provide basis for the preparation of salt-processed Psoraleae Fructus.

MeSH terms

  • Chromatography, High Pressure Liquid
  • Coumarins / analysis
  • Drugs, Chinese Herbal / chemistry*
  • Flavones / analysis
  • Fruit / chemistry*
  • Hot Temperature
  • Phenols / analysis
  • Psoralea / chemistry*
  • Reproducibility of Results
  • Sodium Chloride / chemistry*
  • Technology, Pharmaceutical / methods*

Substances

  • Coumarins
  • Drugs, Chinese Herbal
  • Flavones
  • Phenols
  • Sodium Chloride
  • coumarin
  • flavone