Methylation of the promoter of brain-derived neurotrophic factor exon IV and antidepressant response in major depression

Mol Psychiatry. 2014 Mar;19(3):281-3. doi: 10.1038/mp.2013.58. Epub 2013 May 14.

Authors

A Tadić¹, L Müller-Engling², K F Schlicht¹, A Kotsiari², N Dreimüller¹, A Kleimann², S Bleich², K Lieb¹, H Frieling²

Affiliations

¹ Department of Psychiatry and Psychotherapy, University Medical Centre, Mainz, Germany.
² Molecular Neuroscience Laboratory, Department of Psychiatry, Socialpsychiatry and Psychotherapy, Hannover Medical School (MHH), Hanover, Germany.

PMID: 23670489
DOI: 10.1038/mp.2013.58

No abstract available

Publication types

Letter
Research Support, Non-U.S. Gov't

MeSH terms

Adult
Antidepressive Agents / therapeutic use*
Brain-Derived Neurotrophic Factor / metabolism*
DNA Methylation*
Depressive Disorder, Major / drug therapy*
Depressive Disorder, Major / metabolism*
Exons*
Female
Humans
Male
Promoter Regions, Genetic*
Young Adult

Substances

Antidepressive Agents
Brain-Derived Neurotrophic Factor
BDNF protein, human