Physiological and molecular aspects of degradation of plant polysaccharides by fungi: what have we learned from Aspergillus?

Biotechnol J. 2013 Aug;8(8):884-94. doi: 10.1002/biot.201200382. Epub 2013 May 15.

Abstract

Plant biomass is the most abundant and usable carbon source for many fungal species. Due to its diverse and complex structure, fungi need to produce a large range of enzymes to degrade these polysaccharides into monomeric components. The fine-tuned production of such diverse enzyme sets requires control through a set of transcriptional regulators. Aspergillus has a strong potential for degrading biomass, thus this genus has become the most widely studied group of filamentous fungi in this area. This review examines Aspergillus as a successful degrader of plant polysaccharides, and reviews its potential in many industries such as biofuel and as a production host of homologous and heterologous proteins.

Keywords: Aspergillus; Carbohydrate active enzymes (CAZys); Enzyme production; Gene regulation; Plant polysaccharides.

Publication types

  • Review

MeSH terms

  • Aspergillus / enzymology
  • Aspergillus / genetics
  • Aspergillus / metabolism*
  • Biofuels
  • Biomass
  • Biotechnology / methods*
  • Fungal Proteins / genetics
  • Fungal Proteins / metabolism*
  • Gene Expression Regulation, Fungal
  • Glycoside Hydrolases / genetics
  • Glycoside Hydrolases / metabolism*
  • Plants / chemistry
  • Plants / metabolism*
  • Plants / microbiology*
  • Polysaccharides / metabolism*

Substances

  • Biofuels
  • Fungal Proteins
  • Polysaccharides
  • Glycoside Hydrolases