Effects of hypothetical type 2 diabetes genetic testing on parents' efforts to prevent diabetes in children

Clin Pediatr (Phila). 2013 Sep;52(9):821-8. doi: 10.1177/0009922813488644. Epub 2013 May 14.

Abstract

Objective: To examine the effect of hypothetical genetic susceptibility test results on diabetic parents' intention to prevent type 2 diabetes (T2D) in their children.

Methods: Parents with T2D indicated their intention to prevent T2D in their youngest child at baseline and after a hypothetical positive and negative T2D genetic test result. We calculated mean/median "preventive intention scores" for each scenario and examined the association between parents' score change and parent/child characteristics.

Results: A total of 63% of parents reported that their child had "almost no risk" or "slight risk" of developing T2D. Parents' median baseline preventive intention score was 8. It increased to 10 after a positive test result and decreased to 5 after a negative test result.

Conclusions: Negative T2D genetic susceptibility test results may decrease diabetic parents' intentions to prevent T2D for their children. Future research studies in a real-life clinical context should examine this phenomenon.

Keywords: children; diabetes mellitus; genetic testing; type 2 diabetes; vignettes.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Attitude to Health*
  • Child
  • Diabetes Mellitus, Type 2 / prevention & control*
  • Diabetes Mellitus, Type 2 / psychology*
  • Female
  • Genetic Testing / statistics & numerical data*
  • Humans
  • Intention*
  • Male
  • Middle Aged
  • Parents / psychology*
  • Risk Factors