Clinical drug response to thiopurines is associated to a lower interferon-γ production by IBD patient's T lymphocytes

J Crohns Colitis. 2013 Nov;7(10):e497-8. doi: 10.1016/j.crohns.2013.04.017. Epub 2013 May 16.

Authors

Maria Luisa Dongarrà¹, Alessandra Belvedere, Guido Ferlazzo, Walter Fries

Affiliation

¹ Laboratory of Immunology and Biotherapy, Dept. of Human Pathology, University of Messina, Messina, Italy.

PMID: 23685139
DOI: 10.1016/j.crohns.2013.04.017

No abstract available

Keywords: Azathioprine;; CD4; Inflammatory bowel disease;; Mercaptopurine;.

Publication types

Letter
Comment

MeSH terms

Azathioprine / therapeutic use*
Crohn Disease / drug therapy*
Female
Humans
Immunosuppressive Agents / therapeutic use*
Interferon-gamma / biosynthesis*
Male
T-Lymphocytes / pathology*

Substances

Immunosuppressive Agents
Interferon-gamma
Azathioprine