Abstract
A study shows that circadian glucocorticoid oscillations have dual roles in dendritic spine plasticity. Glucocorticoids control spine formation and elimination through distinct mechanisms, which together are important for motor learning and maintenance.
MeSH terms
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Animals
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Cerebral Cortex / physiology*
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Circadian Rhythm / physiology*
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Dendritic Spines / metabolism*
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Female
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Glucocorticoids / pharmacology*
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Learning / physiology*
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Male
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Neuronal Plasticity / physiology*
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Signal Transduction / physiology*
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Synapses / physiology*