Acute aortic dissection (Stanford type B) during pregnancy

J Perinatol. 2013 Jun;33(6):484-5. doi: 10.1038/jp.2012.123.

Abstract

We report a case of acute aortic dissection (Stanford type B) that occurred in pregnant woman at 34-week gestation. She had no systemic characteristics of Marfan syndrome, however she exhibited a mutation of FBN1, Arg 545 Cys, which has been found to correlate with ectopia lentis but not with aortic dissection.

Publication types

  • Case Reports

MeSH terms

  • Acute Disease
  • Adult
  • Aortic Aneurysm / classification
  • Aortic Aneurysm / diagnosis*
  • Aortic Aneurysm / genetics
  • Aortic Aneurysm / therapy
  • Aortic Dissection / classification
  • Aortic Dissection / diagnosis*
  • Aortic Dissection / genetics
  • Aortic Dissection / therapy
  • Cesarean Section
  • Critical Care
  • DNA Mutational Analysis
  • Echocardiography
  • Ectopia Lentis / genetics
  • Female
  • Fibrillin-1
  • Fibrillins
  • Genetic Carrier Screening
  • Humans
  • Microfilament Proteins / genetics
  • Mutation, Missense
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / diagnosis*
  • Pregnancy Complications, Cardiovascular / genetics
  • Pregnancy Complications, Cardiovascular / therapy
  • Pregnancy Trimester, Third
  • Tomography, X-Ray Computed

Substances

  • FBN1 protein, human
  • Fibrillin-1
  • Fibrillins
  • Microfilament Proteins