Abstract
The Brd4 protein is an epigenetic reader that is central to regulation of cellular transcription and mitotic bookmarking. The transcription and replication proteins of many viruses interact with Brd4. We describe the multiple roles of Brd4 in the papillomavirus lifecycle.
Publication types
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Research Support, N.I.H., Intramural
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Review
MeSH terms
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Cell Cycle Proteins
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Host-Pathogen Interactions*
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Humans
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Models, Biological
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Nuclear Proteins / metabolism*
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Papillomaviridae / physiology*
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Protein Biosynthesis
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Transcription Factors / metabolism*
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Transcription, Genetic
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Viral Proteins / metabolism*
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Virus Replication*
Substances
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BRD4 protein, human
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Cell Cycle Proteins
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Nuclear Proteins
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Transcription Factors
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Viral Proteins