Abstract
“In the search for novel approaches for the treatment of resistant cancers, small molecules targeting the cyclin dependent kinase inhibitors have shown considerable promise”
MeSH terms
-
Antineoplastic Agents / therapeutic use*
-
Apoptosis / drug effects
-
Cell Cycle Checkpoints / drug effects
-
Cyclin-Dependent Kinase Inhibitor p21 / antagonists & inhibitors*
-
Cyclin-Dependent Kinase Inhibitor p21 / genetics
-
Cyclin-Dependent Kinase Inhibitor p21 / metabolism
-
Drug Resistance, Neoplasm
-
Humans
-
Kidney Neoplasms / drug therapy*
-
RNA Interference
-
RNA, Small Interfering / genetics
-
RNA, Small Interfering / metabolism
-
Small Molecule Libraries / chemistry*
-
Small Molecule Libraries / pharmacology
-
Small Molecule Libraries / therapeutic use
Substances
-
Antineoplastic Agents
-
Cyclin-Dependent Kinase Inhibitor p21
-
RNA, Small Interfering
-
Small Molecule Libraries