Pathway Processor 2.0: a web resource for pathway-based analysis of high-throughput data

Bioinformatics. 2013 Jul 15;29(14):1825-6. doi: 10.1093/bioinformatics/btt292. Epub 2013 Jun 5.

Abstract

Summary: Pathway Processor 2.0 is a web application designed to analyze high-throughput datasets, including but not limited to microarray and next-generation sequencing, using a pathway centric logic. In addition to well-established methods such as the Fisher's test and impact analysis, Pathway Processor 2.0 offers innovative methods that convert gene expression into pathway expression, leading to the identification of differentially regulated pathways in a dataset of choice.

Availability and implementation: Pathway Processor 2.0 is available as a web service at http://compbiotoolbox.fmach.it/pathwayProcessor/. Sample datasets to test the functionality can be used directly from the application.

Contact: [email protected]

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • Animals
  • High-Throughput Nucleotide Sequencing*
  • Humans
  • Internet
  • Mice
  • Oligonucleotide Array Sequence Analysis*
  • Rats
  • Software*
  • Transcriptome