Calcifying odontogenic cyst (COC) is an uncommon benign cystic neoplasm of odontogenic origin, which shows extensive diversity in its clinico-pathological appearances and biological behavior. It most commonly occurs in broader age group of 1-82 years in anterior part of jaws which is classically described by presence of ghost cells. There are variants of COC according to clinical, histopathological, and radiological characteristics. Therefore a proper categorization of the cases is needed for better understanding of the pathogenesis of each variant. Here we report a rare case of ameloblastomatous calcifying ghost cell odontogenic cyst in 24 year old female with brief review of literature. Presence of ameloblastomatous proliferation and impacted canine presented a diagnostic dilemma and was diagnosed by careful radiographic and histopathogical interpretation. Long follow up and more case report are required to shed light on its behaviour as there scarcity of data of this lesion in literature.
Keywords: cyst; ghost cells; neoplasm; odontogenic.