Clinical dehydration and glomerular filtration rate in acute paediatric gastroenteritis

Acta Paediatr. 2013 Aug;102(8):e360-2. doi: 10.1111/apa.12293. Epub 2013 Jun 7.

Abstract

Aim: To evaluate changes in glomerular filtration rate in acute gastroenteritis.

Methods: The correlation between two clinical diagnostic scales and glomerular filtration rate has been investigated in 113 children with acute gastroenteritis in a paediatric emergency setting.

Results: A significant reduction of GFR was found in 10% children less than, and 5% children higher than, 2 years of age with acute gastroenteritis.

Conclusion: The differences observed as for risk of renal hypoperfusion suggests to consider the age of children as an important determinant to consider the dehydration status in acute gastroenteritis.

Publication types

  • Comparative Study

MeSH terms

  • Acute Disease
  • Age Factors
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Dehydration / etiology*
  • Dehydration / physiopathology
  • Dehydration / therapy
  • Female
  • Fluid Therapy / methods
  • Gastroenteritis / complications*
  • Gastroenteritis / diagnosis
  • Glomerular Filtration Rate*
  • Humans
  • Infant
  • Male
  • Monitoring, Physiologic
  • Prognosis
  • Reference Values
  • Risk Assessment
  • Severity of Illness Index