Does the placement of a cystic duct tube after a hepatic resection help reduce the incidence of post-operative bile leak?

HPB (Oxford). 2013 Jul;15(7):517-22. doi: 10.1111/j.1477-2574.2012.00611.x. Epub 2012 Nov 19.

Abstract

Background: In this retrospective study, the effects of cystic duct (C) tube use on the incidence of post-hepatectomy bile leak were assessed.

Methods: The subjects were 550 patients who underwent a hepatectomy during 1990-2011, with (n = 83) and without (n = 467) C tube drainage. The use of a C tube was based on the surgeon's choice.

Results: Bile leakage was observed in 44 (8%) patients, and its incidence post-operatively correlated with intrahepatic cholangiocarcinoma, parenchymal transection with forceps fracture and tie, a major hepatectomy, prolonged surgery and excessive blood loss (P < 0.050) but not with the use of a C tube. The incidence of an intra-abdominal infection was higher and the hospital stay was longer in the leak (49 days) than non-leak group (21 days, P < 0.001). ISGLS grade B and C bile leak post-hemi-hepatectomy and extended-hepatectomy were more frequent in the non-C than C tube group (P = 0.016). The duration of hospitalization was not different between the two groups; however, 7 patients in the non-C tube group had prolonged hospitalization (> 60 days) compared with none in the C tube group (P = 0.454).

Conclusion: The usefulness of the C tube in preventing post-hepatectomy bile leak could not be confirmed; however, both bile leak requiring clinical management and long hospitalization after a major hepatectomy could be reduced with C tube use.

MeSH terms

  • Abdominal Abscess / epidemiology
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anastomotic Leak / epidemiology
  • Anastomotic Leak / prevention & control*
  • Biliary Tract Diseases / epidemiology
  • Biliary Tract Diseases / prevention & control*
  • Chi-Square Distribution
  • Cystic Duct / surgery*
  • Drainage / adverse effects
  • Drainage / instrumentation*
  • Female
  • Hepatectomy* / adverse effects
  • Humans
  • Incidence
  • Japan / epidemiology
  • Length of Stay
  • Logistic Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Odds Ratio
  • Proportional Hazards Models
  • Retrospective Studies
  • Risk Factors
  • Time Factors
  • Treatment Outcome
  • Young Adult