The utility of lower endoscopic ultrasound-guided fine needle aspiration for the diagnosis of benign and malignant pelvic diseases

J Clin Gastroenterol. 2014 Feb;48(2):127-30. doi: 10.1097/MCG.0b013e3182951a72.

Abstract

Background: The utility of endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) for the diagnosis of pelvic masses has been suggested but limited data are available in the literature regarding its diagnostic accuracy.

Goals: To report our institutional experience with EUS-FNA for the diagnosis of a variety of pelvic diseases.

Methods: Patients who were referred for the evaluation of pelvic lesions using lower EUS-FNA were included in this retrospective analysis if they had available surgical pathology (obtained after EUS) which was considered the gold standard against which the EUS-FNA findings would have been compared. The diagnostic accuracy of EUS-FNA for pelvic masses was analyzed and any early or late complications after the procedure were reported. A pelvic mass was defined in the study as any mass seen with an imaging modality in the pelvic area including those involving the colonic wall.

Results: Twenty patients had EUS-FNA followed by surgery for whom FNA cytology and surgical pathology findings were available. EUS-FNA reached the correct diagnosis in 19 out of 20 patients, whereas for the missing 1 malignant lymph node wherein FNA revealed benign cytology, surgical specimen confirmed metastatic colon cancer. The sensitivity and specificity of EUS-FNA were 90% and 100%, respectively, with positive and negative predictive values of 100% and 90%, respectively. No early or late complications were encountered with this procedure for the sampling of cystic and noncystic masses.

Conclusions: EUS-FNA has excellent diagnostic accuracy for pelvic masses. It represents a safe procedure with excellent yield and thus may be used as a first line modality for the evaluation and diagnosis of pelvic masses within its reach.

MeSH terms

  • Abscess / diagnostic imaging
  • Abscess / pathology
  • Carcinoma / diagnostic imaging
  • Carcinoma / pathology*
  • Carcinoma / secondary*
  • Colonic Neoplasms / diagnostic imaging
  • Colonic Neoplasms / pathology*
  • Cysts / diagnostic imaging
  • Cysts / pathology
  • Endometrial Neoplasms / diagnostic imaging
  • Endometrial Neoplasms / pathology*
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration* / adverse effects
  • Female
  • Gastrointestinal Neoplasms / diagnostic imaging
  • Gastrointestinal Neoplasms / pathology*
  • Gastrointestinal Stromal Tumors / diagnostic imaging
  • Gastrointestinal Stromal Tumors / pathology*
  • Humans
  • Lymph Nodes / diagnostic imaging
  • Lymph Nodes / pathology*
  • Lymphatic Metastasis
  • Male
  • Predictive Value of Tests
  • Retrospective Studies
  • Urologic Neoplasms / diagnostic imaging
  • Urologic Neoplasms / pathology