Biokinetic analysis code development and applications to visualise the distribution of intake activity

Radiat Prot Dosimetry. 2013 Dec;157(3):323-30. doi: 10.1093/rpd/nct153. Epub 2013 Jun 14.

Abstract

Measurements for internal dose assessment are required to be conducted based on the distribution of radionuclides in the body, which may change depending on the lapsed time. In this study, a biokinetic analysis code, which can be used in practical radiation control is developed, and the results of (60)Co and (137)Cs biokinetics are visualised as examples by drawing the depositions for each organ and tissue in a figure of the body as a function of lapsed time. In addition, based on visualised biokinetics, precautions for in vivo measurements are also discussed. These discussions led to the conclusion that the information of visualised biokinetics is useful for actual measurements in practical radiation control.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Algorithms*
  • Cesium Radioisotopes / analysis
  • Cesium Radioisotopes / pharmacokinetics*
  • Cobalt Radioisotopes / analysis
  • Cobalt Radioisotopes / pharmacokinetics*
  • Computer Simulation
  • Digestive System / radiation effects
  • Environmental Exposure / analysis*
  • Humans
  • Kinetics
  • Models, Biological*
  • Radiation Protection / standards*
  • Relative Biological Effectiveness
  • Respiratory System / radiation effects
  • Tissue Distribution

Substances

  • Cesium Radioisotopes
  • Cobalt Radioisotopes