Transoral partial epiglottidectomy to treat dysphagia in post-treatment head and neck cancer patients: a preliminary report

Laryngoscope. 2014 Mar;124(3):665-71. doi: 10.1002/lary.24278. Epub 2013 Aug 1.

Abstract

Objectives: To determine symptoms and findings in patients with dysphagia related to epiglottic dysfunction. To analyze outcomes in patients who underwent partial epiglottidectomy due to dysphagia related to epiglottic dysfunction.

Study design: Review and analysis of clinical data obtained as part of the diagnosis and treatment of patients with dysphagia related to epiglottic dysfunction.

Methods: A retrospective review was performed of all post-treatment head and neck cancer patients who underwent epiglottidectomy at a single tertiary care referral center. Objective pre- and postprocedure swallow findings, endoscopic evaluation, and subjective improvement based on patient self-reports were reviewed.

Results: Seven patients were identified based on endoscopic evaluation and modified barium swallow study (MBSS) as having epiglottic pathology leading to dysphagia. Specific anatomic and functional findings included thickening of the epiglottis, absence of epiglottic deflection, vallecular bolus retention during and after the swallow, and bolus backflow from the pharynx to the oral or nasal cavity. Partial epiglottidectomy was performed in these patients. Postoperative MBSS was analyzed for changes in swallow efficiency and safety. Nearly all patients demonstrated improved pharyngeal bolus passage with little to no added swallowing morbidity.

Conclusions: Preliminary findings suggest a role for partial epiglottidectomy in post-treatment head and neck cancer patients with swallowing disorders. Ideal candidates have intact tongue base contraction and poor retroflexion of the epiglottis, which results in bolus obstruction at the level of the valleculae. Partial epiglottic resection enables improved bolus passage in the pharyngeal phase. Minimal postoperative morbidity occurs in the appropriately selected patient.

Keywords: Dysphagia; chemotherapy; epiglottectomy; epiglottidectomy; head and neck cancer; quality of life; radiation.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Chemotherapy, Adjuvant
  • Cohort Studies
  • Combined Modality Therapy
  • Deglutition Disorders / etiology
  • Deglutition Disorders / physiopathology
  • Deglutition Disorders / surgery*
  • Epiglottis / physiopathology
  • Epiglottis / surgery*
  • Female
  • Follow-Up Studies
  • Head and Neck Neoplasms / pathology
  • Head and Neck Neoplasms / therapy
  • Humans
  • Laryngoscopy / methods
  • Male
  • Middle Aged
  • Mouth / surgery
  • Oropharyngeal Neoplasms / complications
  • Oropharyngeal Neoplasms / pathology
  • Oropharyngeal Neoplasms / therapy*
  • Postoperative Complications / physiopathology
  • Postoperative Complications / surgery
  • Radiotherapy, Adjuvant
  • Retrospective Studies
  • Risk Assessment
  • Treatment Outcome