Evaluation of cerebral circulation and oxygen metabolism in infants using near-infrared light

Brain Dev. 2014 Apr;36(4):277-83. doi: 10.1016/j.braindev.2013.05.011. Epub 2013 Jun 22.

Abstract

Bedside monitoring of cerebral circulation or oxygen metabolism in infants to appropriately manage circulation and establish the oxygen dose, aiming at improving the neurological prognosis, is needed in general clinical practice. Near-infrared spectroscopy is used for measurements of neonatal cerebral Hb oxygen saturation, cerebral blood volume, cerebral blood flow and cerebral metabolic rate of oxygen. Near-infrared time-resolved spectroscopy is particularly useful for bedside evaluation of cerebral circulation and oxygen metabolism because of its simple measurement procedure. Combined evaluation of cerebral blood volume and cerebral Hb oxygen saturation is expected to contribute to treatment centering on the brain in neonatal medical care.

Keywords: Cerebral Hb oxygen saturation; Cerebral blood flow; Cerebral blood volume; Near-infrared spectroscopy; Near-infrared time-resolved spectroscopy; Neonates.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Blood Volume Determination / methods
  • Brain / blood supply
  • Brain / physiology*
  • Cerebrovascular Circulation / physiology*
  • Humans
  • Infant
  • Infant, Newborn
  • Oxygen / blood*
  • Oxygen Consumption
  • Spectroscopy, Near-Infrared / methods*

Substances

  • Oxygen