Candida pneumonia in a term infant after prolonged use of inhaled corticosteroids for bronchopulmonary dysplasia (BPD)

Early Hum Dev. 2013 Jun:89 Suppl 1:S62-3. doi: 10.1016/S0378-3782(13)70018-5.

Abstract

Candida spp. frequently cause invasive fungal disease in neonates, and many organs or apparatus can be involved through bloodstream dissemination. Though Candida spp. can heavily colonize the upper and lower respiratory tract, an end-organ localization to the lung is not frequent and acquisition via descending/respiratory route is a questioned entity. Here we report the case of a young infant affected by bronchopulmonary dysplasia (BPD) and treated with inhaled steroids who developed Candida pneumonia likely acquired through descending route.

Publication types

  • Case Reports

MeSH terms

  • Administration, Inhalation
  • Anti-Bacterial Agents / therapeutic use
  • Antifungal Agents / therapeutic use
  • Bronchopulmonary Dysplasia / complications*
  • Bronchopulmonary Dysplasia / drug therapy
  • Candidiasis / complications*
  • Candidiasis / immunology
  • Glucocorticoids / adverse effects*
  • Humans
  • Infant
  • Infant, Newborn
  • Inhalation Exposure
  • Lung
  • Lung Diseases, Fungal / immunology
  • Lung Diseases, Fungal / microbiology*
  • Lung Diseases, Fungal / therapy
  • Male
  • Oxygen Inhalation Therapy
  • Respiratory Insufficiency / immunology
  • Respiratory Insufficiency / microbiology
  • Respiratory Insufficiency / therapy
  • Term Birth*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Glucocorticoids