In hematopoietic cells with a germline mutation of CBL, loss of heterozygosity is not a signature of juvenile myelo-monocytic leukemia

Leukemia. 2013 Dec;27(12):2404-7. doi: 10.1038/leu.2013.203. Epub 2013 Jul 4.

Authors

M Strullu¹, A Caye, B Cassinat, O Fenneteau, F Touzot, T Blauwblomme, R Rodriguez, S Latour, A Petit, V Barlogis, C Galambrun, T Leblanc, A Baruchel, C Chomienne, H Cavé

Affiliation

¹ 1] Department of Genetics, Assistance Publique-Hôpitaux de Paris (AP-HP) Robert Debré Hospital, Paris, France [2] INSERM UMR_S940, Institut Universitaire d'Hématologie (IUH), Université Paris-Diderot Sorbonne-Paris-Cité, Paris, France.

PMID: 23823657
DOI: 10.1038/leu.2013.203

No abstract available

Publication types

Letter

MeSH terms

Bone Marrow Cells / pathology*
Child, Preschool
Female
Germ-Line Mutation*
Humans
Infant
Leukemia, Myelomonocytic, Juvenile / genetics*
Loss of Heterozygosity*
Male
Pedigree
Proto-Oncogene Proteins c-cbl / genetics*

Substances

Proto-Oncogene Proteins c-cbl
CBL protein, human