Synthesis and local anesthetic activity of (E)- and (Z)-diethylaminoethyliminothers of 1,8-naphtyridine

P L Ferrarini; C Mori; N Tellini

Synthesis and local anesthetic activity of (E)- and (Z)-diethylaminoethyliminothers of 1,8-naphtyridine

Farmaco. 1990 Mar;45(3):385-9.

Authors

P L Ferrarini¹, C Mori, N Tellini

Affiliation

¹ Istituto di Chimica Farmaceutica Dell'Università di Pisa, Italy.

PMID: 2383350

Abstract

A series of (E)- and (Z)-diethylaminoethylimino ethers of 1.8-naphthyridine was prepared and characterized. Preliminary studies showed that none of the tested compounds presented noteworthy local anesthetic activity.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Anesthetics, Local / chemical synthesis*
Animals
Chemical Phenomena
Chemistry
Cornea / drug effects
Imines / chemical synthesis
Imines / pharmacology
Naphthyridines / chemical synthesis*
Naphthyridines / pharmacology
Rabbits

Substances

Anesthetics, Local
Imines
Naphthyridines