Dibenzocyclooctane lignans from the stems of Schisandra wilsoniana

Planta Med. 2013 Aug;79(12):1051-5. doi: 10.1055/s-0032-1328747. Epub 2013 Jul 9.

Abstract

Five new dibenzocyclooctane lignans, schisanwilsonins K-O, together with eighteen known lignans were isolated from the stems of Schisandra wilsoniana. The structures of these new compounds were elucidated by spectroscopic methods, including 2D-NMR techniques. Several compounds were found to show anti-HIV and anti-HBV activity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-HIV Agents / chemistry*
  • Anti-HIV Agents / isolation & purification
  • Anti-HIV Agents / pharmacology
  • Antiviral Agents / chemistry*
  • Antiviral Agents / isolation & purification
  • Antiviral Agents / pharmacology
  • Cyclooctanes / chemistry
  • Cyclooctanes / isolation & purification
  • Cyclooctanes / pharmacology
  • Lignans / chemistry*
  • Lignans / isolation & purification
  • Lignans / pharmacology
  • Magnetic Resonance Spectroscopy
  • Molecular Structure
  • Plant Stems / chemistry
  • Plants, Medicinal
  • Schisandra / chemistry*

Substances

  • Anti-HIV Agents
  • Antiviral Agents
  • Cyclooctanes
  • Lignans