Arterial spin labeling (ASL) perfusion: techniques and clinical use

J-C Ferré; E Bannier; H Raoult; G Mineur; B Carsin-Nicol; J-Y Gauvrit

doi:10.1016/j.diii.2013.06.010

Arterial spin labeling (ASL) perfusion: techniques and clinical use

Diagn Interv Imaging. 2013 Dec;94(12):1211-23. doi: 10.1016/j.diii.2013.06.010. Epub 2013 Jul 11.

Authors

J-C Ferré¹, E Bannier, H Raoult, G Mineur, B Carsin-Nicol, J-Y Gauvrit

Affiliation

¹ CHU de Rennes, Department of Radiology, Hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France; Plateforme Neurinfo, CHU de Rennes, Hôpital Pontchaillou, 2, rue Henri-Le-Guilloux, 35033 Rennes cedex 9, France; INRIA, VisAGeS unité/projet U746, 35042 Rennes, France; INSERM VisAGeS unité/projet U746, UMR 6074, Irisa, Université Rennes 1, 35043 Rennes cedex, France. Electronic address: [email protected].

PMID: 23850321
DOI: 10.1016/j.diii.2013.06.010

Abstract

Arterial spin labeling (ASL) perfusion is a MRI technique to quantify tissue blood flow. ASL is a non-invasive technique that labels the protons in the arterial blood by radiofrequency pulses, without the exogenous injection of contrast media. This article has three goals: 1) present the principles of ASL perfusion, the types of labeling and the ways to obtain the mapping; 2) specify and the quality criteria for the mapping obtained, while emphasizing the artifacts; and 3) describe the main encephalic and renal applications.

Keywords: Brain; Kidney; MRI; Perfusion.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Arteries
Brain / blood supply
Humans
Kidney / blood supply
Magnetic Resonance Imaging / methods*
Perfusion Imaging / methods*
Protons
Regional Blood Flow* / physiology

Substances

Protons