Tandem Suzuki-Miyaura coupling/acid-catalyzed cyclization between vinyl ether boronates and vinyl halides: a concise approach to polysubstituted furans

Org Lett. 2013 Aug 2;15(15):3840-3. doi: 10.1021/ol4014574. Epub 2013 Jul 15.

Abstract

Polysubstituted 2-(ω-hydroxyalkyl)furans were prepared by tandem Suzuki-Miyaura coupling/acid-catalyzed cyclization starting from appropriately substituted 3-haloallylic alcohols and dihydrofuran-, dihydropyran- or glycal-derived pinacol boronates.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acids
  • Boronic Acids / chemistry*
  • Catalysis
  • Cyclization
  • Furans
  • Halogens / chemistry*
  • Molecular Structure
  • Vinyl Compounds / chemistry*

Substances

  • Acids
  • Boronic Acids
  • Furans
  • Halogens
  • Vinyl Compounds