MAPping the genomic landscape of low-grade pediatric gliomas

Nat Genet. 2013 Aug;45(8):847-9. doi: 10.1038/ng.2706.

Abstract

Two recent large-scale sequencing studies have identified multiple genetic aberrations in pediatric low-grade gliomas. These findings offer substantial insights that may spur the development of new diagnostics and treatments for these cancers.

Publication types

  • News
  • Comment

MeSH terms

  • Animals
  • Astrocytoma / genetics*
  • Brain Neoplasms / genetics*
  • Humans
  • Mutation*
  • Receptor, Fibroblast Growth Factor, Type 1 / genetics*
  • Receptor, trkB / genetics*

Substances

  • Receptor, Fibroblast Growth Factor, Type 1
  • Receptor, trkB