[Candida albicans endocarditis after treatment of complete atrioventricular canal]

J Mycol Med. 2013 Sep;23(3):185-8. doi: 10.1016/j.mycmed.2013.06.004. Epub 2013 Jul 26.
[Article in French]

Abstract

Infective endocarditis is rare in children, it is rarer after a surgical treatment of atrioventricular canal, and it is exceptional that Candida albicans is the etiologic agent. This is a serious infection found in congenital heart disease with or without surgery. It is potentially lethal, despite diagnostic and therapeutic advances. We report a case of infective endocarditis due to C. albicans after the treatment of a congenital systemic atrioventricular canal in a child with trisomy 21. The diagnosis was suspected on clinical manifestations and cardiac auscultation. Confirmation was provided by positive blood cultures and echocardiography. The large size of the vegetation in the patient was in favor of a fungal etiology, blood cultures allowed to identify the fungus. This observation illustrates a poorly understood disease, with very poor prognosis and which is a potential complication of heart surgery. The improved prognosis should be achieved by shortening the time to diagnosis and optimizing the therapeutic support.

Keywords: Atrioventricular canal; Canal atrioventriculaire; Candida albicans; Child; Endocardite fongique; Fungal endocarditis; Pédiatrie.

Publication types

  • Case Reports

MeSH terms

  • Candida albicans* / isolation & purification
  • Candidiasis / complications*
  • Candidiasis / microbiology
  • Child, Preschool
  • Down Syndrome / complications
  • Down Syndrome / surgery
  • Endocarditis / complications
  • Endocarditis / microbiology*
  • Fatal Outcome
  • Heart Septal Defects
  • Humans
  • Male
  • Mitral Valve Insufficiency / complications
  • Mitral Valve Insufficiency / surgery*
  • Postoperative Complications / microbiology

Supplementary concepts

  • Complete atrioventricular septal defect