A case of hypocomplementaemic urticarial vasculitis with a high serum level of rheumatoid factor

Australas J Dermatol. 2013 Aug;54(3):e62-3. doi: 10.1111/j.1440-0960.2011.00873.x. Epub 2012 Feb 23.

Abstract

We report a case of hypocomplementaemic urticarial vasculitis with an elevated serum rheumatoid factor level. Hypocomplementaemic urticarial vasculitis is an immune complex-mediated disease characterised by urticarial eruptions. High levels of rheumatoid factor may be associated with hypocomplementaemia due to the consumption of complement, because the rheumatoid factor can form immune complexes with immunoglobulin. It is necessary to pay attention to the amounts of complement in cases of urticarial eruptions with elevated rheumatoid factor level. The eruptions were relieved with a combination of prednisolone and colchicine.

Keywords: colchicine; hypocomplementaemia; purpura; rheumatoid factor; urticarial vasculitis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Inflammatory Agents
  • Colchicine
  • Complement System Proteins / deficiency*
  • Female
  • Gout Suppressants / therapeutic use
  • Humans
  • Prednisolone / therapeutic use
  • Rheumatoid Factor / blood*
  • Urticaria / blood*
  • Urticaria / drug therapy
  • Urticaria / pathology
  • Vasculitis / blood*
  • Vasculitis / drug therapy
  • Vasculitis / pathology

Substances

  • Anti-Inflammatory Agents
  • Gout Suppressants
  • Complement System Proteins
  • Rheumatoid Factor
  • Prednisolone
  • Colchicine