Abstract
Albumin is one of the most extensively studied endogenous proteins which are used in the fabrication of drug delivery and diagnostic technologies during last 10 years. This review provides a summary of products involving the use of albumin as a drug delivery tool for getting better the pharmacokinetics of a drug by developing the targetted drug delivery systems and diagnosing the pathologies. Using albumin, following market approved products have been developed: Levemir and Victoza (antidiabetic product), Abraxane (antimetastatic breast cancer product), and Nanocoll and Albures (for lymphoscintigraphy and diagnosis of cancer and rheumatoid arthritis).
MeSH terms
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Albumin-Bound Paclitaxel
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Albumins / administration & dosage*
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Albumins / chemistry
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Animals
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Antineoplastic Agents / administration & dosage
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Antineoplastic Agents / chemistry
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Chemistry, Pharmaceutical
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Drug Carriers*
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Glucagon-Like Peptide 1 / administration & dosage
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Glucagon-Like Peptide 1 / analogs & derivatives
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Glucagon-Like Peptide 1 / chemistry
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Humans
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Hypoglycemic Agents / administration & dosage
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Hypoglycemic Agents / chemistry
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Insulin Detemir
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Insulin, Long-Acting / administration & dosage
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Insulin, Long-Acting / chemistry
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Liraglutide
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Paclitaxel / administration & dosage
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Paclitaxel / chemistry
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Predictive Value of Tests
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Radiopharmaceuticals
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Technetium Tc 99m Aggregated Albumin
Substances
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Albumin-Bound Paclitaxel
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Albumins
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Antineoplastic Agents
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Drug Carriers
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Hypoglycemic Agents
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Insulin, Long-Acting
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Radiopharmaceuticals
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Technetium Tc 99m Aggregated Albumin
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technetium Tc 99m nanocolloid
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Insulin Detemir
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Liraglutide
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Glucagon-Like Peptide 1
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Paclitaxel