Highly sensitive detection of self-aggregated single-walled carbon nanotubes using a DNA-immobilized resonator

Kuewhan Jang; Jinsung Park; Doyeon Bang; Sangmyung Lee; Juneseok You; Seungjoo Haam; Sungsoo Na

doi:10.1039/c3cc42911c

Highly sensitive detection of self-aggregated single-walled carbon nanotubes using a DNA-immobilized resonator

Chem Commun (Camb). 2013 Oct 7;49(77):8635-7. doi: 10.1039/c3cc42911c.

Authors

Kuewhan Jang¹, Jinsung Park, Doyeon Bang, Sangmyung Lee, Juneseok You, Seungjoo Haam, Sungsoo Na

Affiliation

¹ Department of Mechanical Engineering, Korea University, Seoul 136-701, Republic of Korea. [email protected].

PMID: 23926595
DOI: 10.1039/c3cc42911c

Abstract

By using DNA linkers, we are able to conjugate self-crosslinked SWNTs which could be detected upon hybridization with a DNA immobilized resonator. The DNA immobilized resonator is able to detect SWNTs with a detection limit of 10 ng ml(-1) which was 2-3 orders of magnitude smaller than the reported SWNT toxicity concentration.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Biosensing Techniques / methods*
DNA / chemistry*
Limit of Detection
Models, Molecular
Nanotubes, Carbon / analysis*

Substances

Nanotubes, Carbon
DNA