Hematogones: an overview

Leuk Res. 2013 Nov;37(11):1404-11. doi: 10.1016/j.leukres.2013.07.024. Epub 2013 Aug 8.

Abstract

Hematogones were initially described as mysterious cells in bone marrow smears more than 70 years ago. These cells are normal bone marrow B-lymphocyte precursors with properties that overlap those of lymphoblasts. Their morphological and immunological features are described here with an update on the knowledge of hematogones in hematological and non-hematological disorders.

Keywords: B-cell precursors; Bone marrow transplantation; Hematogones; Hematological recovery.

Publication types

  • Review

MeSH terms

  • Animals
  • Hematologic Neoplasms / diagnosis*
  • Humans
  • Precursor Cells, B-Lymphoid / pathology*