High-dose melphalan produces favorable response in a patient with multiple myeloma and coexisting essential thrombocythemia with JAK2 mutation

Bone Marrow Transplant. 2014 Jan;49(1):148-9. doi: 10.1038/bmt.2013.117. Epub 2013 Aug 12.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Bone Marrow / pathology
  • Female
  • Granulocyte Colony-Stimulating Factor / chemistry
  • Hematopoietic Stem Cell Mobilization
  • Hematopoietic Stem Cell Transplantation
  • Humans
  • Hydroxyurea / therapeutic use
  • Janus Kinase 2 / genetics*
  • Melphalan / administration & dosage*
  • Middle Aged
  • Multiple Myeloma / complications
  • Multiple Myeloma / genetics*
  • Multiple Myeloma / therapy*
  • Mutation
  • Myeloablative Agonists / administration & dosage
  • Platelet Count
  • Thrombocythemia, Essential / complications
  • Thrombocythemia, Essential / genetics*
  • Thrombocythemia, Essential / therapy*
  • Treatment Outcome

Substances

  • Myeloablative Agonists
  • Granulocyte Colony-Stimulating Factor
  • JAK2 protein, human
  • Janus Kinase 2
  • Melphalan
  • Hydroxyurea