The role of magnetic nanoparticles in the localization and treatment of breast cancer

Biomed Res Int. 2013:2013:281230. doi: 10.1155/2013/281230. Epub 2013 Jul 9.

Abstract

The role of magnetic nanoparticles (MNPs) in medical applications is rapidly developing. Advances in nanotechnology are bringing us closer to the development of dual and multifunctional nanoparticles that are challenging the traditional distinction between diagnostic and treatment agents. The current use of MNPs in breast cancer falls into four main groups: (1) imaging of primary and metastatic disease, (2) sentinel lymph node biopsy (SLNB), (3) drug delivery systems, and (4) magnetic hyperthermia. The current evidence for the use of MNPs in these fields is mounting, and potential cutting-edge clinical applications, particularly with relevance to the fields of breast oncological surgery, are emerging.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Breast Neoplasms / diagnosis*
  • Breast Neoplasms / drug therapy*
  • Breast Neoplasms / pathology
  • Diagnostic Imaging
  • Drug Delivery Systems
  • Female
  • Humans
  • Hyperthermia, Induced
  • Magnetite Nanoparticles / administration & dosage*
  • Magnetite Nanoparticles / therapeutic use
  • Sentinel Lymph Node Biopsy

Substances

  • Magnetite Nanoparticles