Successful treatment of cerebral venous thrombosis associated with ulcerative colitis

J Stroke Cerebrovasc Dis. 2013 Nov;22(8):e684-6. doi: 10.1016/j.jstrokecerebrovasdis.2013.07.023. Epub 2013 Aug 9.

Abstract

Thromboembolic complications, such as deep venous thrombosis and pulmonary embolism, are well described in patients with inflammatory bowel disease, but cerebral venous thrombosis (CVT) is a rare but potentially devastating complication. The authors describe the case of a 36-year-old Japanese man presenting with CVT associated with ulcerative colitis (UC) that was successfully treated with a combination of continuous anticoagulant and pulse steroid therapy. Our observations suggest that aggressive therapy for inducing acute UC remission is vitally important for CVT associated with UC.

Keywords: Cerebral venous thrombosis; anticoagulant therapy; headache; steroid; ulcerative colitis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Inflammatory Agents / administration & dosage*
  • Anticoagulants / therapeutic use*
  • Colitis, Ulcerative / complications
  • Colitis, Ulcerative / diagnosis
  • Colitis, Ulcerative / drug therapy*
  • Diffusion Magnetic Resonance Imaging
  • Gastrointestinal Agents / administration & dosage*
  • Humans
  • Intracranial Thrombosis / diagnosis
  • Intracranial Thrombosis / drug therapy*
  • Intracranial Thrombosis / etiology
  • Male
  • Phlebography
  • Pulse Therapy, Drug
  • Steroids / administration & dosage*
  • Treatment Outcome
  • Venous Thrombosis / diagnosis
  • Venous Thrombosis / drug therapy*
  • Venous Thrombosis / etiology

Substances

  • Anti-Inflammatory Agents
  • Anticoagulants
  • Gastrointestinal Agents
  • Steroids