Gene of the month: E-cadherin (CDH1)

J Clin Pathol. 2013 Nov;66(11):928-32. doi: 10.1136/jclinpath-2013-201768. Epub 2013 Aug 12.

Authors

Tamara M H Gall¹, Adam E Frampton

Affiliation

¹ HPB Surgical Unit, Department of Surgery & Cancer, Imperial College, Hammersmith Hospital campus, , London, UK.

PMID: 23940132
DOI: 10.1136/jclinpath-2013-201768

No abstract available

Keywords: Cancer; Cancer Genetics; Carcinoma; Cell Adhesion Molecules; Metastasis.

Publication types

Review

MeSH terms

Adherens Junctions / metabolism
Antigens, CD
Cadherins / chemistry
Cadherins / genetics*
Cadherins / metabolism*
Cell Adhesion
Cell Differentiation
Chromosomes, Human, Pair 16 / genetics
DNA Methylation
Epithelial Cells / metabolism
Epithelial-Mesenchymal Transition / physiology*
Humans
Loss of Heterozygosity
Multiprotein Complexes / genetics
Multiprotein Complexes / metabolism
Neoplasms / genetics*
Neoplasms / therapy
Promoter Regions, Genetic / genetics
Signal Transduction
Tumor Suppressor Proteins / chemistry
Tumor Suppressor Proteins / genetics
Tumor Suppressor Proteins / metabolism*

Substances

Antigens, CD
CDH1 protein, human
Cadherins
Multiprotein Complexes
Tumor Suppressor Proteins