Of origins and pedigrees: lineage tracing of dendritic cells

Carmen Gerlach; Aude Thiriot; Ulrich H von Andrian

doi:10.1016/j.cell.2013.07.044

Of origins and pedigrees: lineage tracing of dendritic cells

Cell. 2013 Aug 15;154(4):720-2. doi: 10.1016/j.cell.2013.07.044.

Authors

Carmen Gerlach¹, Aude Thiriot, Ulrich H von Andrian

Affiliation

¹ Department of Microbiology and Immunobiology, Division of Immunology, Harvard Medical School, Boston, MA 02115, USA.

PMID: 23953106
DOI: 10.1016/j.cell.2013.07.044

Abstract

Understanding the ontogeny of distinct hematopoietic cell types remains a challenge. In this issue, Schraml et al. contribute to unraveling the complexity of a central component of the mononuclear phagocyte system by using a new in vivo approach to trace the progeny of common dendritic cell precursors.

Publication types

Comment

MeSH terms

Animals
Cell Lineage*
Dendritic Cells / cytology*
Lectins, C-Type / metabolism*
Receptors, Immunologic / metabolism*

Substances

Clec9a protein, mouse
Lectins, C-Type
Receptors, Immunologic